featuring
Eric Wohleb, PhDUniversity of Cincinnati College of MedicineJoin us for a live presentation and Q&A
on
Thursday, February 13, 2025
11:00 AM - 12:00 PM ET
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The Role of Glia in Stress- and Drug-induced Synaptic Plasticity and Behavior This webinar will focus on recent work showing that stress- and drug-induced changes in synaptic plasticity and behavior are accompanied by phenotypic and functional alterations in microglia and astrocytes. Mechanistic studies indicate that these glial responses are mediated by interactions with neurons and contribute to subsequent synaptic changes and associated behaviors. This work is significant as it provides new insight into the mechanisms regulating neuronal structure and behavior, which can guide new approaches targeting these cellular pathways for therapeutic utility. Eric Wohleb, is an Associate Professor in the Department of Pharmacology, Physiology, & Neurobiology at the University of Cincinnati College of Medicine (UCCOM). Dr. Wohleb obtained his PhD in Neuroscience from the Ohio State University, working in the labs of Dr. Jonathan Godbout and Dr. John Sheridan at the Institute for Behavioral Medicine Research. He then continued his training as a Postdoctoral Research Assistant and Associate Research Scientist under the mentorship of Dr. Ronald Duman in the Division of Molecular Psychiatry at the Yale School of Medicine. These experiences provided Dr. Wohleb with unique training in neuroimmunology, molecular neurobiology, and neuropharmacology. Current research in the Wohleb Lab seeks to integrate these perspectives to better understand the role of neuroimmune interactions in physiological and pathological conditions. To this end, the Wohleb Lab uses cutting-edge molecular and cellular approaches to study microglia and astrocytes in the neurobiological and behavioral effects of chronic stress, antidepressant administration, and stroke. Dr. Wohleb’s work has been supported with funding from the National Institutes of Health, Brain and Behavior Research Foundation, and the UC College of Medicine. He has also received several honors and awards including the Chair’s Choice Fellowship from the Society of Biological Psychiatry, Robert Ader New Investigator Award from the Psychoneuroimmunology Research Society, Rising Star Award from the UC College of Medicine, and selected as an Associate Member of the American College of Neuropsychopharmacology. Most relevant to this series, Dr. Wohleb joined PNIRS in 2009 as a predoctoral trainee and received generous support from the Society and all of its wonderful mentors throughout his career development. He is glad to maintain his PNIRS membership and pay back this support (in part) by serving on the Scientific Affairs, Nominating, Membership, Financial, and Training Committees over the years. Webpage: https://med.uc.edu/depart/ppn/research/faculty-research-labs/wohleb-lab/home
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